2025 Jan 14 - Unlock the role of spatial profiling in detecting diverse mRNA markers and short targets implicated in obesity at single-cell resolution
Claudia A. Doege, MD
Associate Professor of Pathology and Cell Biology Columbia University
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Jyoti Sheldon, B.D.S, MS
Sr. Product Marketing Manager ACD, a Bio-Techne brand
Outline:
During this seminar, we will explore the role of RNAscope™ spatial profiling in mapping diverse RNA markers implicated in body weight regulation and their impact in obesity research. RNAscope in situ hybridization (ISH) spatial technology provides a powerful method to detect gene expression within the morphological tissue context. The proprietary “double Z” probe design in combination with the advanced signal amplification enables highly specific and sensitive detection of the target RNA with each dot visualizing a single RNA transcript. This robust signal-to-noise technology allows for the detection of gene transcripts at the single molecule level providing clear answers while seamlessly fitting into existing anatomic pathology workflows.
